Peptides and Aptamers Targeting HSP70: A Novel Approach for Anticancer Chemotherapy
نویسندگان
چکیده
منابع مشابه
Correction: peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy.
The inhibition of heat shock protein 70 (HSP70) is an emerging strategy in cancer therapy. Unfortunately, no specific inhibitors are clinically available. By yeast two-hybrid screening, we have identified multiple peptide aptamers that bind HSP70. When expressed in human tumor cells, two among these peptide aptamers-A8 and A17-which bind to the peptide-binding and the ATP-binding domains of HSP...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2011
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-10-1443